Primary Identifier | MGI:1346329 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 24111 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable hormone activity. Predicted to be involved in several processes, including regulation of blood pressure; regulation of circadian sleep/wake cycle; and regulation of heart rate. Predicted to be active in extracellular space. Is expressed in several structures, including Harderian gland; alimentary system; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in gestational diabetes; hypertension; and type 2 diabetes mellitus. Orthologous to human UTS2 (urotensin 2). PHENOTYPE: Homozygous inactivation of this gene leads to alterations in macrophage and hepatic cholesterol homeostasis. [provided by MGI curators] |