Primary Identifier | MGI:2446217 | Organism | mouse, laboratory |
Chromosome | 4 | NCBI Gene Number | 230936 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity; chromatin-protein adaptor activity; and methylated histone binding activity. Predicted to be involved in mitotic chromosome condensation and regulation of DNA repair. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; early conceptus; ganglia; genitourinary system; and sensory organ. Orthologous to human PHF13 (PHD finger protein 13). PHENOTYPE: Mice homozygous for a gene trap allele exhibit reduced male fertility over time associated with impaired spermatogonial stem cell differentiation and male germ cell apoptosis. [provided by MGI curators] |