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Protein Coding Gene : Mxra8 matrix-remodelling associated 8

Primary Identifier  MGI:1922011 Organism  mouse, laboratory
Chromosome  4 NCBI Gene Number  74761
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in establishment of glial blood-brain barrier. Located in cell surface. Is expressed in brain ventricle and choroid plexus; cerebral cortex ventricular layer; heart valve; meninges; and skeleton. Orthologous to human MXRA8 (matrix remodeling associated 8).
PHENOTYPE: Phenotypic analysis of mice homozygous for a gene trap allele indicates this mutation has no notable phenotype in any parameter tested in a high-throughput screen. Mice homozygous for two alleles with intragenic deletions in the Ig-like domain 2 show decreased infection of musculoskeletal tissues with various alphaviruses. [provided by MGI curators]
  • synonyms:
  • Mxra8,
  • matrix-remodelling associated 8,
  • AI131686,
  • 1200013A08Rik,
  • RIKEN cDNA 1200013A08 gene,
  • MGI:2140196,
  • RIKEN cDNA 1700095D18 gene,
  • Asp3,
  • expressed sequence AI131686,
  • limitrin,
  • DICAM,
  • MGI:1920805,
  • 1700095D18Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For