Primary Identifier | MGI:1918240 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 545725 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable double-stranded DNA binding activity. Predicted to be involved in DNA geometric change and termination of mitochondrial transcription. Located in mitochondrion. Orthologous to human MTERF1 (mitochondrial transcription termination factor 1). PHENOTYPE: Mice homozygous for a knock-out allele of both Mterf1a and Mterf1b exhibit impaired transcription initiation at light-strand promoters resulting in a decrease of de novo transcription and reduced 7S RNA. [provided by MGI curators] |