Primary Identifier | MGI:1196625 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 14362 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Wnt-protein binding activity. Involved in several processes, including astrocyte-dopaminergic neuron signaling; negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway; and regulation of presynapse assembly. Acts upstream of or within several processes, including hard palate development; heart morphogenesis; and negative regulation of signal transduction. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skin. Orthologous to human FZD1 (frizzled class receptor 1). PHENOTYPE: Homozygous mutation of this gene does not appear to result in a phenotype. [provided by MGI curators] |