| Primary Identifier | MGI:1929288 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 64945 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity. Predicted to be involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules. Located in lateral plasma membrane and tight junction. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and integumental system. Orthologous to human CLDN12 (claudin 12). PHENOTYPE: Homozygotes for a knock-out allele show no signs of blood-brain barrier tight junction dysfunction under healthy or neuroinflammatory conditions. However, subtle and mostly sex specific alterations associated with CNS, energy metabolism, and cardiovascular functions are observed. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
