| Primary Identifier | MGI:2443778 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 207686 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in several processes, including positive regulation of fertilization; positive regulation of flagellated sperm motility; and response to odorant. Acts upstream of or within sperm axoneme assembly. Located in non-motile cilium. Is expressed in several structures, including brain; genitourinary system; gut gland; nasal cavity epithelium; and spinal cord ventricular layer. Used to study spermatogenic failure 24. Human ortholog(s) of this gene implicated in spermatogenic failure 24. Orthologous to human CFAP69 (cilia and flagella associated protein 69). PHENOTYPE: Homozygous loss-of-function mutations in this gene result in male sterility associated with severe asthenoteratospermia and multiple morphological abnormalities of the sperm flagella. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
