Primary Identifier | MGI:96283 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 15563 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable Gi/o-coupled serotonin receptor activity and neurotransmitter receptor activity. Acts upstream of or within adenylate cyclase-activating G protein-coupled receptor signaling pathway. Predicted to be located in perikaryon. Predicted to be active in dendrite and postsynaptic specialization membrane. Is expressed in several structures, including adipose tissue; alimentary system; brain; genitourinary system; and liver and biliary system. Orthologous to human HTR5A (5-hydroxytryptamine receptor 5A). PHENOTYPE: The are conflicting reports about mice with homozygous null alleles regarding increased exploratory behavior and an abnormal exploratory behavior response to LSD. [provided by MGI curators] |