| Primary Identifier | MGI:1934960 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 69852 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II-specific DNA-binding transcription factor binding activity and transcription regulator inhibitor activity. Involved in negative regulation of muscle cell differentiation and negative regulation of transcription by RNA polymerase II. Located in euchromatin. Is expressed in central nervous system and genitourinary system. Orthologous to human TCF23 (transcription factor 23). PHENOTYPE: Female mice homozygous for a knock-out allele and older than 4 months of age show subfertility characterized by reduced gestational weight gain, decreased litter size, thin myometrium with a disorganized collagen matrix and discontinuous smooth muscle sheets, and impaired parturition with high rates of dystocia, resulting in significant fetal demise. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
