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Protein Coding Gene : Fndc4 fibronectin type III domain containing 4
Primary Identifier  MGI:1917195 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  64339
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in negative regulation of inflammatory response. Located in endoplasmic reticulum; extracellular space; and plasma membrane. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human FNDC4 (fibronectin type III domain containing 4).
PHENOTYPE: Homozygous knockout mice suffer from increased severity of DSS-induced colitis with increased weight loss and decreased colon length. [provided by MGI curators]
  • synonyms:
  • expressed sequence AI838506,
  • FRCP1,
  • MGI:2140974,
  • 2810430J06Rik,
  • AW487863,
  • AI838506,
  • RIKEN cDNA 2810430J06 gene,
  • Fndc4,
  • fibronectin type III domain containing 4,
  • 6330410H20Rik,
  • MGI:1927605,
  • MGI:1921251,
  • expressed sequence AW487863,
  • MGI:2141194,
  • RIKEN cDNA 6330410H20 gene
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5 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

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Genes/Features --> Phenotypes (MP terms)

Disease

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