| Primary Identifier | MGI:99147 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 22612 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables protein tyrosine kinase activity. Acts upstream of or within several processes, including cellular response to retinoic acid; cellular response to transforming growth factor beta stimulus; and positive regulation of peptidyl-tyrosine phosphorylation. Located in actin filament and plasma membrane. Is expressed in several structures, including 2-cell stage conceptus; 4-8 cell stage conceptus; blastocyst-stage conceptus; central nervous system; and morula-stage conceptus. Orthologous to human YES1 (YES proto-oncogene 1, Src family tyrosine kinase). PHENOTYPE: Homozygotes for targeted null alleles have no overt phenotype, but mice homozygous for both Yes and Src null mutations exhibit impaired movement and breathing, resulting in perinatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
