| Primary Identifier | MGI:1201685 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 13016 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; chromatin binding activity; and lncRNA binding activity. Involved in negative regulation of DNA-templated transcription; synaptic vesicle cycle; and white fat cell differentiation. Acts upstream of or within Notch signaling pathway and negative regulation of transcription by RNA polymerase II. Located in nucleus. Part of transcription repressor complex. Is active in GABA-ergic synapse; glutamatergic synapse; and presynaptic active zone cytoplasmic component. Is expressed in several structures, including central nervous system; chorionic plate; genitourinary system; limb; and lung. Orthologous to human CTBP1 (C-terminal binding protein 1). PHENOTYPE: Mice homozygous for a knock-out allele display partial postnatal lethality and decreased body size. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
