Primary Identifier | MGI:1859281 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 54426 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and zymogen activation. Located in rough endoplasmic reticulum. Is expressed in brain; liver; liver left lobe; liver right lobe; and metanephros. Orthologous to human HGFAC (HGF activator). PHENOTYPE: Homozygous null mice display impaired intestinal regeneration and increased mortality after intestinal injury. [provided by MGI curators] |