Primary Identifier | MGI:87936 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 11553 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables G protein-coupled receptor activity. Acts upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in axon terminus; cytoplasm; and neuronal cell body. Predicted to be active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including adrenal gland; central nervous system; early embryo; oocyte; and sensory organ. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human ADRA2C (adrenoceptor alpha 2C). PHENOTYPE: Mice homozygous for targeted mutations that inactivate the gene are viable and fertile and appear grossly normal. [provided by MGI curators] |