| Primary Identifier | MGI:1334417 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 17713 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including ATPase binding activity; adenyl-nucleotide exchange factor activity; and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrion. Is expressed in several structures, including adrenal gland; alimentary system; bone; midbrain ventricular layer; and submandibular gland primordium. Orthologous to human GRPEL1 (GrpE like 1, mitochondrial). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality prior to E8.5. Mice homozygous for a conditional allele activated in skeletal muscle cells exhibit weight loss, skeletal muscle atrophy and fibrosis, and alterations glycolysis and fatty acid levels in muscle fibers. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
