| Primary Identifier | MGI:2442640 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231207 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nucleic acid binding activity and ribosome binding activity. Involved in cellular response to hypoxia; negative regulation of cytoplasmic translation; and regulation of translation at synapse, modulating synaptic transmission. Acts upstream of or within negative regulation of translational elongation. Located in cytoplasm and ribosome. Is active in glutamatergic synapse. Is expressed in central nervous system; early conceptus; and olfactory epithelium. Orthologous to human CPEB2 (cytoplasmic polyadenylation element binding protein 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit early postnatal lethality, decreased heart rate, and increased parasympathetic signaling leading to increased pulmonary acetylcholine level, bronchoconstriction, severe apnea, and abnormal breathing patterns. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
