Primary Identifier | MGI:1096350 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 14181 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables fibroblast growth factor binding activity. Acts upstream of or within positive regulation of fibroblast growth factor receptor signaling pathway and positive regulation of myoblast proliferation. Located in cell surface and extracellular region. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and skin. Orthologous to human FGFBP1 (fibroblast growth factor binding protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit abnormal neuromuscular synapse morphology and accelerates progression of ALS. [provided by MGI curators] |