| Primary Identifier | MGI:1914249 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 66999 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin binding activity. Acts upstream of or within negative regulation of smooth muscle cell differentiation and somatic stem cell population maintenance. Located in cortical actin cytoskeleton. Is expressed in several structures, including alimentary system; eye; male reproductive gland or organ; nervous system; and neural ectoderm. Orthologous to human MED28 (mediator complex subunit 28). PHENOTYPE: Embryos homozygous for a knock-out allele exhibit disorganized extraembryonic tissues, failure to form an egg cylinder, absent embryonic epiblast, and peri-implantation lethality resulting from the loss of pluripotency of the inner cell mass. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
