| Primary Identifier | MGI:1315205 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 20563 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables chemorepellent activity. Involved in aortic valve morphogenesis; pulmonary valve morphogenesis; and ventricular septum morphogenesis. Acts upstream of or within several processes, including mammary duct terminal end bud growth; negative regulation of axon extension; and nervous system development. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb; and sensory organ. Used to study Kartagener syndrome; cystic kidney disease; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human SLIT2 (slit guidance ligand 2). PHENOTYPE: Homozygous mutants display perinatal lethality, abnormal ureteric bud development, multiple fused kidneys, multiple ureters, and hydroureter. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
