Primary Identifier | MGI:1278335 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 16924 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables PDZ domain binding activity; identical protein binding activity; and ubiquitin-protein transferase activity. Involved in synapse maturation. Acts upstream of or within ubiquitin-dependent protein catabolic process. Located in cytoplasm. Is active in hippocampal mossy fiber to CA3 synapse and postsynapse. Is expressed in several structures, including brain; genitourinary system; liver; nasal epithelium; and spleen. Orthologous to human LNX1 (ligand of numb-protein X 1). PHENOTYPE: Mice homozygous for a targeted mutation exhibit an increased percentage of B1-like B cells in peritoneal lavage when compared with that of controls. [provided by MGI curators] |