| Primary Identifier | MGI:1926078 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 59040 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable guanyl ribonucleotide binding activity; metal ion binding activity; and ribonucleoside triphosphate phosphatase activity. Predicted to be involved in several processes, including mitochondrial outer membrane permeabilization; mitochondrion transport along microtubule; and regulation of mitochondrion organization. Located in mitochondrion. Is expressed in brain. Used to study motor neuron disease. Orthologous to human RHOT1 (ras homolog family member T1). PHENOTYPE: Mice homozygous for a null allele die neonatally exhibiting cyanosis, respiratory failure, loss of brainstem cranial motor neurons, decreased cervical motor neuron number and phrenic nerve branching, and alterations in retrograde mitochondrial transport and run length in cortical axons. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
