Primary Identifier | MGI:1914306 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 56412 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity. Involved in mitochondrial ribosome assembly. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; nervous system; and skeleton. Orthologous to human NOA1 (nitric oxide associated 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit embryonic lethality during organogenesis associated with developmental retardation, decreased cell proliferation and apoptosis, increased cell necrosis, and abnormal mitochondrial morphology and physiology. [provided by MGI curators] |