Primary Identifier | MGI:1926193 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 56792 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables macrophage colony-stimulating factor receptor binding activity and transmembrane receptor protein tyrosine kinase adaptor activity. Involved in several processes, including negative regulation of macrophage colony-stimulating factor signaling pathway; negative regulation of macrophage migration; and negative regulation of ruffle assembly. Acts upstream of or within response to bacterium. Predicted to be located in several cellular components, including centriolar satellite; mitochondrion; and nucleoplasm. Predicted to be part of protein-containing complex. Orthologous to human STAP1 (signal transducing adaptor family member 1). PHENOTYPE: Mice homozygous for a null allele show no overt phenotype with no alterations in plasma lipid levels. [provided by MGI curators] |