| Primary Identifier | MGI:1860130 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 104443 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to be located in actin cytoskeleton. Predicted to be active in plasma membrane. Is expressed in brain; dorsal root ganglion; and trigeminal ganglion. Orthologous to human NPFFR2 (neuropeptide FF receptor 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased litter size and sex-specific increased susceptibility to diet-induced obesity and adipose accumulation, impaired diet-induced thermogenesis, and altered bone thickness. [provided by MGI curators] |