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Protein Coding Gene : Npffr2 neuropeptide FF receptor 2

Primary Identifier  MGI:1860130 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  104443
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable G protein-coupled receptor activity and peptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway and cellular response to hormone stimulus. Predicted to act upstream of or within signal transduction. Predicted to be located in actin cytoskeleton. Predicted to be active in plasma membrane. Is expressed in brain; dorsal root ganglion; and trigeminal ganglion. Orthologous to human NPFFR2 (neuropeptide FF receptor 2).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased litter size and sex-specific increased susceptibility to diet-induced obesity and adipose accumulation, impaired diet-induced thermogenesis, and altered bone thickness. [provided by MGI curators]
  • synonyms:
  • neuropeptide FF receptor 2,
  • G protein-coupled receptor 74,
  • Gpr74,
  • Npffr2,
  • NPFF2

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

8 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For