| Primary Identifier | MGI:1860203 | Organism | mouse, laboratory |
| Chromosome | 5 | Mgi Type | polymorphic pseudogene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable CXCR3 chemokine receptor binding activity; chemokine activity; and heparin binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; T cell chemotaxis; and positive regulation of release of sequestered calcium ion into cytosol. Predicted to be located in extracellular space. Is expressed in head; nasal cavity epithelium; palatal shelf epithelium; palatal shelf mesenchyme; and testis. Orthologous to human CXCL11 (C-X-C motif chemokine ligand 11). PHENOTYPE: Mice with null or restored expression show similar adaptive immune responses to viral infection. [provided by MGI curators] |
| specificity | BALB/c mice produce a functional protein from the Cxcl11 locus, but a single nucleotide deletion in the C57BL/6J genome introduces a frameshift resulting in early translation termination and renders the allele null. |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
