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Protein Coding Gene : Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11

Primary Identifier  MGI:2149821 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  114664
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable estradiol 17-beta-dehydrogenase [NAD(P)+] activity. Predicted to be involved in androgen catabolic process. Predicted to be located in cytoplasm. Predicted to be active in lipid droplet. Is expressed in several structures, including alimentary system; brain; genitourinary system; liver; and sensory organ. Orthologous to human HSD17B11 (hydroxysteroid 17-beta dehydrogenase 11).
PHENOTYPE: Homozygous mutant mice exhibit an increased mean serum IgG2a response to ovalbumin challenge and an increased mean percentage of immature B cells in bone marrow. [provided by MGI curators]
  • synonyms:
  • Dhrs8,
  • dehydrogenase/reductase (SDR family) member 8,
  • retSDR2,
  • hydroxysteroid (17-beta) dehydrogenase 11,
  • Hsd17b11,
  • Pan1b,
  • 17beta-HSD11

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

3 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

5 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For