Primary Identifier | MGI:1923671 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 76421 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in reciprocal meiotic recombination and synaptonemal complex assembly. Located in chromosome. Is expressed in gonad; liver; spleen; and uterus. Orthologous to human C1orf146 (chromosome 1 open reading frame 146). PHENOTYPE: Mice homozygous for a knock-out allele exhibit infertility due to desynapsis during meiosis and apoptosis of male germ cells and absent oocyte at P6. [provided by MGI curators] |