| Primary Identifier | MGI:87941 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 320129 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables G protein-coupled receptor kinase activity. Predicted to be involved in several processes, including desensitization of G protein-coupled receptor signaling pathway; inositol phosphate metabolic process; and rhodopsin metabolic process. Predicted to act upstream of or within phosphorylation. Predicted to be located in several cellular components, including Z disc; dendrite; and sperm midpiece. Predicted to be active in glutamatergic synapse; postsynaptic density; and presynapse. Is expressed in several structures, including adrenal gland; gut gland; nervous system; submandibular gland primordium; and thymus primordium. Orthologous to human GRK3 (G protein-coupled receptor kinase 3). PHENOTYPE: Animals homozygous for a mutation of this gene appear normal and are fertile, but exhibit a lack of odorant receptor-mediated desensitization in the olfactory epithelium. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
