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Protein Coding Gene : Iscu iron-sulfur cluster assembly enzyme
Primary Identifier  MGI:1913633 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  66383
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein homodimerization activity. Involved in [4Fe-4S] cluster assembly. Located in mitochondrion. Part of mitochondrial [2Fe-2S] assembly complex. Orthologous to human ISCU (iron-sulfur cluster assembly enzyme).
PHENOTYPE: Homozygous null embryos die prior to implantation. [provided by MGI curators]
  • synonyms:
  • NifU-like N-terminal domain containing,
  • Nifun,
  • Iscu,
  • iron-sulfur cluster assembly enzyme,
  • MGI:2147429,
  • RIKEN cDNA 2310020H20 gene,
  • expressed sequence AA407971,
  • AA407971,
  • 2310020H20Rik
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Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

Trail: ProteinCodingGene

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

Trail: ProteinCodingGene

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For





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