Primary Identifier | MGI:2180849 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 231655 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables double-stranded RNA binding activity. Involved in interleukin-27-mediated signaling pathway. Predicted to be located in cytoplasm and nucleolus. Predicted to be active in cytosol; membrane; and nucleoplasm. Is expressed in testis. Orthologous to human OASL (2'-5'-oligoadenylate synthetase like). PHENOTYPE: Mice with a deletion of this gene have increased expression of type I interferon and show increased resistance to viral infection. [provided by MGI curators] |