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Protein Coding Gene : Adam1a a disintegrin and metallopeptidase domain 1a
Primary Identifier  MGI:2429504 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  280668
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable metalloendopeptidase activity. Acts upstream of or within binding activity of sperm to zona pellucida. Located in membrane raft. Orthologous to human ADAM1A (ADAM metallopeptidase domain 1A (pseudogene)).
PHENOTYPE: Homozygous null mice display male infertility with asthenozoospermia. [provided by MGI curators]
  • synonyms:
  • Ftna,
  • Adam1,
  • a disintegrin and metallopeptidase domain 1a,
  • expressed sequence AW050088,
  • AW050088,
  • PH-30 alpha,
  • MGI:2141140,
  • fertilin alpha,
  • MGI:104722,
  • Adam1a,
  • MGD-MRK-27085
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0 Canonical

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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

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Disease

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