| Primary Identifier | MGI:1928375 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 56378 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be a structural constituent of cytoskeleton. Predicted to contribute to actin filament binding activity. Involved in regulation of synaptic vesicle endocytosis. Located in lamellipodium. Is expressed in lower jaw tooth and tooth. Orthologous to human ARPC3 (actin related protein 2/3 complex subunit 3). PHENOTYPE: Mice homozygous for a transposon-induced allele develop only to the blastocyst stage and show defects in trophoblast outgrowth and in the dynamics of actin accumulation. Mice heterozygous for the same transposon-induced allele and a knock-out allele showimpaired trophoblast outgrowth activity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
