| Primary Identifier | MGI:1345629 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 23912 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Predicted to be involved in several processes, including actin filament organization; regulation of actin cytoskeleton organization; and signal transduction. Predicted to be located in cytoplasm and cytoskeleton. Predicted to be active in cytosol and plasma membrane. Orthologous to human RHOF (ras homolog family member F, filopodia associated). PHENOTYPE: Mice homozygous for a knock-out allele exhibit macrothrombocytopenia without an effect on filopodia generation. Homozygous knockout also leads to the reduction of the number of B cells in the spleen marginal zone. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
