Primary Identifier | MGI:1352504 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 29816 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including SH3 domain binding activity; clathrin adaptor activity; and protein dimerization activity. Involved in several processes, including positive regulation of clathrin coat assembly; regulation of actin filament organization; and regulation of gastric acid secretion. Acts upstream of or within receptor-mediated endocytosis. Located in several cellular components, including apical plasma membrane; clathrin-coated pit; and perinuclear region of cytoplasm. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and sensory organ. Orthologous to human HIP1R (huntingtin interacting protein 1 related). PHENOTYPE: Mice homozygous for disruptions in this gene display no abnormal phenotype. [provided by MGI curators] |