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Protein Coding Gene : Mphosph9 M-phase phosphoprotein 9

Primary Identifier  MGI:2443138 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  269702
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Involved in negative regulation of cilium assembly. Located in centrosome. Is expressed in embryo. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human MPHOSPH9 (M-phase phosphoprotein 9).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit a twisted body axis at midgestation, decreased weight and an increased percentage of ciliated cells in the proximal and distal tubules. [provided by MGI curators]
  • synonyms:
  • MGI:2141191,
  • MGI:1922504,
  • Mphosph9,
  • expressed sequence C87456,
  • RIKEN cDNA B930097C17 gene,
  • AW413446,
  • B930097C17Rik,
  • RIKEN cDNA 9630025B04 gene,
  • C87456,
  • M-phase phosphoprotein 9,
  • expressed sequence AW547060,
  • expressed sequence AW413446,
  • MPP-9,
  • RIKEN cDNA 4930548D04 gene,
  • MGI:3035377,
  • MPP9,
  • 9630025B04Rik,
  • AW547060,
  • MGI:2141219,
  • 4930548D04Rik

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2 Involved In Mutations

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