Primary Identifier | MGI:1202069 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 13445 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA polymerase binding activity. Acts upstream of or within face morphogenesis and in utero embryonic development. Predicted to be located in several cellular components, including chromatin; nucleoplasm; and perinuclear region of cytoplasm. Predicted to be part of NuRD complex. Predicted to be active in cytoplasm and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; dentate gyrus subgranular zone; and retina. Orthologous to human CDK2AP1 (cyclin dependent kinase 2 associated protein 1). PHENOTYPE: Mic homozygous for a knock-out allele die between E3.5 and E5.5 with rare survivors exhibiting craniofacial defect. [provided by MGI curators] |