| Primary Identifier | MGI:3028576 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 208144 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable U3 snoRNA binding activity and helicase activity. Predicted to be involved in brain development; positive regulation of male gonad development; and ribosome biogenesis. Predicted to be located in cytoplasm and nuclear membrane. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Human ortholog(s) of this gene implicated in 46,XY sex reversal. Orthologous to human DHX37 (DEAH-box helicase 37). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality before implantation. In vitro outgrowth assays show that embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming blastocysts. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
