Primary Identifier | MGI:1298231 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 22021 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein-tyrosine sulfotransferase activity. Involved in peptidyl-tyrosine sulfation and post-translational protein modification. Is active in Golgi lumen and trans-Golgi network. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human TPST1 (tyrosylprotein sulfotransferase 1). PHENOTYPE: Homozygous null mice exhibit reduced body weight but develop normally. Homozygous females produce smaller sized litters than control females. [provided by MGI curators] |