Primary Identifier | MGI:1298231 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 22021 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables protein-tyrosine sulfotransferase activity. Involved in post-translational protein modification. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma. Orthologous to human TPST1 (tyrosylprotein sulfotransferase 1). PHENOTYPE: Homozygous null mice exhibit reduced body weight but develop normally. Homozygous females produce smaller sized litters than control females. [provided by MGI curators] |