Primary Identifier | MGI:2155987 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 140904 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Located in trans-Golgi network membrane. Is expressed in central nervous system and retina. Orthologous to human CALN1 (calneuron 1). PHENOTYPE: Mice homozygous for a null allele exhibit fewer Golgi satellites and decreased levels of polysialylation of NCAM in distal dendrites of hippocampal CA1 neurons that receive input from the temporoammonic pathway and reduced long-term potentiation at distal synapses. [provided by MGI curators] |