Primary Identifier | MGI:1329044 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 12739 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules; cell junction maintenance; and epithelial cell development. Located in apicolateral plasma membrane; bicellular tight junction; and lateral plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; nose; and urinary system. Orthologous to human CLDN3 (claudin 3). PHENOTYPE: Mice homozygous for a null allele are fertile with mutant males exhibiting normal spermatogenesis and fully functional Sertoli cell tight junctions. [provided by MGI curators] |