| Primary Identifier | MGI:1313278 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 14371 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables Wnt receptor activity. Involved in several processes, including bone regeneration; negative regulation of skeletal muscle acetylcholine-gated channel clustering; and positive regulation of canonical Wnt signaling pathway. Acts upstream of or within B cell differentiation; learning or memory; and neuroblast proliferation. Located in filopodium membrane and perinuclear region of cytoplasm. Is expressed in several structures, including central nervous system; embryo mesenchyme; gonad; sensory organ; and skeleton. Used to study Williams-Beuren syndrome. Orthologous to human FZD9 (frizzled class receptor 9). PHENOTYPE: Mice homozygous for one allele exhibit immune system abnormalities while another null allele causes neurological abnormalities. A third null mutation results in growth retardation and abnormalities in bone mineralization. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
