Primary Identifier | MGI:2664992 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 215061 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and ubiquitin protein ligase activity. Acts upstream of or within regulation of establishment of protein localization. Located in aggresome. Is expressed in brain; liver; and reproductive system. Orthologous to several human genes including TRIM50 (tripartite motif containing 50). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired secretion of gastric acid with impaired stimulated tubulovesicular dynamics. [provided by MGI curators] |