| Primary Identifier | MGI:1345171 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 23921 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transmembrane receptor protein tyrosine kinase adaptor activity. Involved in intracellular signal transduction. Acts upstream of or within several processes, including B-1 B cell homeostasis; brown fat cell differentiation; and cell surface receptor signaling pathway. Located in actin filament; ruffle; and stress fiber. Is expressed in dorsal aorta. Orthologous to human SH2B2 (SH2B adaptor protein 2). PHENOTYPE: Inactivation of this gene results in increased insulin sensitivity accompanied by hypoinsulinemia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
