| Primary Identifier | MGI:1347008 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 26433 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables procollagen glucosyltransferase activity and procollagen-lysine 5-dioxygenase activity. Involved in hydroxylysine biosynthetic process and peptidyl-lysine hydroxylation. Acts upstream of or within several processes, including chordate embryonic development; endothelial cell morphogenesis; and extracellular matrix organization. Located in several cellular components, including endoplasmic reticulum; extracellular space; and trans-Golgi network. Is expressed in several structures, including branchial arch; ear; future brain; incisor; and skeleton. Orthologous to human PLOD3 (procollagen-lysine,2-oxoglutarate 5-dioxygenase 3). PHENOTYPE: Homozygous null mice display embryonic lethality, reduced embryonic growth, fragility, and fragmented basement membranes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
