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Protein Coding Gene : Zcwpw1 zinc finger, CW type with PWWP domain 1

Primary Identifier  MGI:2685899 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  381678
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables histone reader activity and methylated histone binding activity. Involved in meiosis I; positive regulation of DNA metabolic process; and spermatogenesis. Acts upstream of or within homologous chromosome pairing at meiosis. Located in XY body and nucleus. Is expressed in brain; lung; reproductive system; and thymus. Orthologous to human ZCWPW1 (zinc finger CW-type and PWWP domain containing 1).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit male and female infertility due to arrested male meiosis and premature ovarian insufficiency. [provided by MGI curators]
  • synonyms:
  • Gm1053,
  • gene model 1053, (NCBI),
  • Zcwpw1,
  • LOC381678,
  • zinc finger, CW type with PWWP domain 1

Features --> Cross References

Genome

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Mouse features --> Functions (GO terms)

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Disease

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