Primary Identifier | MGI:1924104 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 76854 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables nuclear estrogen receptor activity. Involved in several processes, including cellular response to estradiol stimulus; positive regulation of cell communication; and regulation of primary metabolic process. Located in cytoplasm and plasma membrane. Is active in hippocampal mossy fiber to CA3 synapse. Is expressed in embryo; metanephros; pituitary gland; stomach glandular region epithelium; and stomach glandular region gastric gland. Orthologous to human GPER1 (G protein-coupled estrogen receptor 1). PHENOTYPE: Mice homozygous for a knockout allele exhibit decreased thymic atrophy, insulin, and glucagon responses following treatment with PGE2. [provided by MGI curators] |