| Primary Identifier | MGI:2442032 | Organism | mouse, laboratory |
| Chromosome | 5 | NCBI Gene Number | 231871 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables monoacylglycerol lipase activity and triacylglycerol lipase activity. Involved in positive regulation of triglyceride catabolic process; regulation of inflammatory response; and unsaturated fatty acid metabolic process. Acts upstream of or within cannabinoid biosynthetic process; monoacylglycerol biosynthetic process; and neuroblast proliferation. Predicted to be located in nucleoplasm. Predicted to be active in plasma membrane. Is expressed in brain; liver; and spinal cord. Orthologous to human DAGLB (diacylglycerol lipase beta). PHENOTYPE: Mice homozygous for null mutations have a reduction in endocannabinoids in the brain and a decrease in adult neuronal proliferation in the hippocampus. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
