Primary Identifier | MGI:101909 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 14738 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables phosphatidylcholine binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway and intracellular calcium ion homeostasis. Predicted to be active in cytoplasm and plasma membrane. Is expressed in central nervous system; gut; and liver. Used to study obesity. Orthologous to human GPR12 (G protein-coupled receptor 12). PHENOTYPE: Homozygous mutation of this gene results in obesity, increased cholesterol, glucose and triglyceride levels and decreased energy expenditure. [provided by MGI curators] |